Dr. Kellie Raydon Allay's Science advisor shares her knowledge regarding how safe are CBD Topicals?
ENDOCANNABINOIDS
Cannabis has been used for more than twelve thousand years and for many different purposes (i.e. fiber, medicinal, recreational). However, the endocannabinoid signaling system has only recently been the focus of medical research and considered a potential therapeutic target.
Endocannabinoids mimic the pharmacological actions of the psychoactive principle of marijuana. They are are endogenous lipid-signaling molecules, and generated in the cell membrane from phospholipid precursors and possess cannabimimetic properties. They bind and activate one or more cannabinoid receptor subtypes. Endocannabinoids are implicated in different physiological and pathological functions (regulation of food intake, immunomodulation, inflammation, analgesia, cancer, addictive behavior, epilepsy, and others. The overall goal is to understand the physiological role of the endogenous ligands at different levels of the pain pathway and in different models of pathological pain. |
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CANNABIS VS. HEMP
Fundamentally, both hemp and marijuana are the same plant: Cannabis sativa. There's evidence of Cannabis sativa being grown in Asia thousands of years ago for its fiber and nutritional value.Humans eventually realized that the flowering tops of the plant had psychoactive properties. As humans have done with so many crops, Cannabis farmers began cultivating plants to enhance specific properties.
Hemp – A plant primarily cultivated outside the United States (although a few U.S. states allow it to be grown for research purposes) for use in clothing, paper, biofuels, bioplastics, dietary supplements, cosmetics, and foods. Hemp is cultivated outdoors as a large crop with both male and female plants being present to foster pollination and increase seed production.Legally imported industrial hemp contains less than 0.3% of the psychoactive compound tetrahydrocannabinol (THC). In fact, legally imported hemp will usually specifically eliminate any extracts from the plant’s dried flowering tops. Marijuana (Marihuana) – Cannabis sativa specifically cultivated to enhance its THC content to be used for medicinal or recreational purposes. Marijuana plants are typically grown indoors, under controlled conditions, and growers remove all the male plants from the crop to prevent fertilization, which lowers the plant’s THC level.
Hemp – A plant primarily cultivated outside the United States (although a few U.S. states allow it to be grown for research purposes) for use in clothing, paper, biofuels, bioplastics, dietary supplements, cosmetics, and foods. Hemp is cultivated outdoors as a large crop with both male and female plants being present to foster pollination and increase seed production.Legally imported industrial hemp contains less than 0.3% of the psychoactive compound tetrahydrocannabinol (THC). In fact, legally imported hemp will usually specifically eliminate any extracts from the plant’s dried flowering tops. Marijuana (Marihuana) – Cannabis sativa specifically cultivated to enhance its THC content to be used for medicinal or recreational purposes. Marijuana plants are typically grown indoors, under controlled conditions, and growers remove all the male plants from the crop to prevent fertilization, which lowers the plant’s THC level.
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