✨ G I V E A W A Y ✨ // MIND YOUR BODY !
During the change of seasons and with holidays fast approaching, it’s especially important to put self-care on top of your list! We’ve partnered with 3 amazing brands to get your mind and body ready for Autumn. Enter for a chance to win $300+ worth of wellness products to treat yourself!⠀⠀
The winner 💫 will receive all of the following products:⠀
ALLAY: ALLAY Muscle Recovery Body Butter with 20gm of CBD -Hemp. Organic and vegan. 🏃♀️🏃♂️
SPORTLAND TEA CO: instant Matcha + CBD blend!
Organic teas designed to improve performance. 🍵
Clean energy for all athletes. 🏃♀️🏃♂️
VELOBAR CBD: Great-tasting CBD Protein Bar for Relaxation and Recovery. Organic, Vegan, non-GMO, Gluten-Free. 🏃♀️🏃♂️ Rules: (1) Open to anyone 18 years or older. US/CND citizens only. (2) Giveaway ends Tuesday 10/22 at 12:00 PM PST. (3) Winner will be chosen randomly and announced on Wednesday 10/23 via Instagram.
This giveaway is in no way sponsored, endorsed, or administered by, or in association with, Instagram.
Shop Now: https://www.allaytopicals.com/products.html
#giveawaycontest #selfcaregiveaway #skincaregiveaway #selfcaredaily #skincarediary #meditationstation #meditationcushion #selfcareroutine #selfcarefirst #selfcareday #selfcaretime #contestday #cbd #cbdoil #getcanapa #allaycbd #topshelf #fall
In last week’s blog readers learned how to avoid buying CBD with false or misleading labels, choosing the safest and most effective CBD product. But the question still stands; what type of CBD should I buy?
CBD products range anywhere from bath bombs, to smokable oils, to CBD capsules. Choosing the right product and method of administration plays a direct and important role in its effectiveness.
In this post, we’ll go over the four most common methods of administration, and how to know which one is best for you. In the end, the choice is up to you. If one product hasn't been working the way you’d like it to, switch it up! Try out different products with different extraction methods and methods of administration. Just make sure to always check for a CofA, and make sure what you’re buying is extracted from USDA certified organic hemp.
Understanding the endocannabinoid system
To understand exactly why the method of administration matters, we first have to understand how CBD works within our bodies.
It all starts with the endocannabinoid system…
The endocannabinoid system is a molecular system within the human body that works to maintain balance and homeostasis. This system includes endocannabinoids (these are naturally occurring cannabinoids within our bodies), enzymes, and receptors that cannabinoids bind to.
We have much to learn about the exact function of the endocannabinoid system- what we do know is that it’s responsible for regulating and protecting the function of many important systems. The endocannabinoid system affects our cognitive processes, appetite, memory, fertility, and more.
This system is the whole reason we experience any psychological and medicinal effects of CBD and THC.
So, what happens when you use CBD?
To take affect, CBD molecules must enter the bloodstream and bind to receptors within your endocannabinoid system (CB1 and CB2 receptors), as well as other non cannabinoid receptors- like your serotonin receptor.
The ease with which your CBD product transfers from the site of application into your bloodstream is known as the product's bioavailability. The easier it is for a product to enter your bloodstream and bind to it’s relevant receptors, the more effective it will be.
Now that we have a grasp on the way in which CBD interacts with our bodies, let’s go over some of the main methods of administration!
Oral ingestion of CBD includes CBD capsules and edibles.
Before being absorbed into our bloodstream, CBD molecules must pass through our digestive system and into the liver, where they are then broken down and metabolized. This process is known as first-pass metabolism, or the first pass effect.
During this process, enzymes in the liver break down CBD, greatly reducing its concentration before entering the bloodstream. For this reason, orally ingested CBD typically has very low bioavailability.
Many companies have taken measures to counteract this problem. Namely, companies have begun to make water soluble CBD.
CBD is typically hydrophobic, meaning that it doesn't mix with water. During the production of water-soluble CBD, however, CBD molecules are broken up (and I mean really broken up- into less than 100 nanometers) and suspended in water. This allows for the CBD molecules to be more easily absorbed into our bloodstream, thereby increasing bioavailability and effectiveness.
Even so, orally administered CBD generally has
Sublingual CBD is anything administered under the tongue. This includes tinctures, concentrates and oral sprays.
When sublingually administered, some of the CBD is absorbed directly into the bloodstream through the membrane under the tongue, while some is swallowed (and undergoes first-pass metabolism).
Because some of the CBD is able to bypass first-pass metabolism, sublingual CBD has a much higher biovailability than orally administered CBD, making it significantly more effective. Like orally administered CBD, you can find water soluble sublingual CBD with an even higher bioavailability.
The downside to water-soluble, sublingual CBD is that production costs are high, meaning that products are generally more expensive.
Inhalation involves any CBD product which is consumed by vaporizing or smoking CBD.
The membrane of our lungs is highly permeable, allowing CBD molecules pass into the bloodstream with ease. This means that inhalation boasts a high level of availability, and a very quick onset.
There are, however, risks associated with smoking or vaporizing of any product- including CBD. For one, companies can use artificial and harmful thinning agents to vape oils- namely, polyethylene glycol and propylene glycol. When smoked at high temperatures, these compounds may break down into harmful carcinogens.
Many companies claim that propylene glycol is harmless, but research backing this assertion is limited. In one study conducted on mice, researchers found that the propylene glycol and glycerol have negative and unsuspected effects on our circadian rhythm, directly affecting the onset of various psychiatric and metabolic diseases. Other studies have linked propylene glycol to an increase in asthmatic symptoms and other respiratory conditions.
One way to avoid this problem is to look for products made with vegetable glycerin, or simply smoke CBD 'flower,' or CBD plant matter. Even so, inhalation is not advisable for everyone. If you do choose to buy CBD concentrate, vape, juice, or flower make sure to consult your doctor before hand.
Topical CBD includes CBD administered directly onto the skin using any sort of lotion, balm, or salve.
There are cannabinoid receptors (CB1 and CB2) all throughout our skin, making CBD lotions and balms a viable and effective method of administration. When applied directly to the skin CBD molecules are able to bypass the liver and bind directly to the receptors in our skin, avoiding the first-pass effect.
The benefits of CBD lotion are localized- meaning that rubbing CBD lotion on your knee may not help manage anxiety or increase memory. That being said, CBD lotion is the best option for local ailments (such as back pain, arthritis, wrinkles, acne, wounds, and more).
Numerous studies have found that topically applied CBD is effective in treating localized ailments and serious skin conditions. One study conducted by La Clinica Terapeutica concludes that “the topical administration of CBD ointment [...] is a safe and effective non-invasive alternative to improve the quality of life in patients with some skin disorders, especially of inflammatory background” (B. Palmieri et. al). In an article about the clinical benefits of CBD, Dr. Anup Mulakaluri, ND, discusses the advantages of topically applied CBD on his patients, stating “many of my clients who use cannabis for medicinal purposes, use it topically. They gain great benefit for their mobility, balance, and pain management with topical applications of salve and oils."
Because the lotion has to permeate the skin to reach it’s relevant receptors, it’s important to use enough product- really lather it on. This can be a downside with some CBD products, which tend to make your skin a little oily, especially if you use a lot.
But no worries, ALLAY has your back- our lotion glides on beautifully and soaks right in, letting you feel the benefits of CBD without sticky or greasy skin.
So, what does all this mean? How do you know which CBD product is really right for you?
It depends on what you’re using it for.
If you’re looking for something to help improve your memory, manage mood disorders, or effect any non-localized ailments, water-soluble sublingual CBD is probably best. It has some of the highest bioavailability, quickest onset, and most long-lasting effects.
If you’re looking for something to treat a localized ailment or any sort of skin condition, look no further than topical CBD.
Allay creates potent, highly effective CBD topicals that soak right through your skin, effectively treating whatever ails you while leaving you with soft, happy skin!
Lechasseur, Ariane, et al. “Exposure to Electronic Cigarette Vapors Affects Pulmonary and Systemic Expression of Circadian Molecular Clock Genes.” Physiological Reports, vol. 5, no. 19, 5 Oct. 2019, doi:10.14814/phy2.13440.
Mulakaluri, Anup. “Clinical Application of Cannabis, Cannabiniods (CBD).” Natural Rhythms Integrative Medicine, 11 Dec. 2017, https://nrimseattle.com/blog/2017/11/27/clinical-application-cannabis-cbd/.
PALMIERI, B.; LAURINO, C.; VADALÀ, M.. A therapeutic effect of cbd-enriched ointment in inflammatory skin diseases and cutaneous scars. La Clinica Terapeutica, [S.l.], v. 170, n. 2, p. e93 - e99, apr. 2019. ISSN 1972-6007.
Pond, SM, and TM Tozer. “First-Pass Elimination. Basic Concepts and Clinical Consequences.” PubMed, National Center for Biotechnology Information (NCBI), Jan. 1984, https://www.ncbi.nlm.nih.gov/pubmed/6362950.
CBD’s antioxidant, anti-inflammatory, and moisturizing properties help effectively combat wrinkles as well as other signs of aging.
Although there are many factors that may increase the prominence and onset of wrinkles, those creases in your skin are a natural sign of aging. A side effect of living a full life on this earth. If, however, you are bothered by your wrinkles, here’s what you need to know:
As people age, our skin becomes less elastic, losing its ability to heal, fight inflammation, and retain moisture. Meanwhile, a decreased production of natural oils dries out skin. This is where CBD comes in. In this post, we are going to look at three main properties, all of which directly address and combat the root causes of aging skin.
All of these factors play an important role in combating the production and appearance of wrinkles- but it doesn’t stop there.
A lot of CBD’s effectiveness for treating skin has to do with our own endocannabinoid system. This system, which is present in our skin, works in harmony with the cannabinoids found in the cannabis plant (including CBD). By introducing compounds such as CBD, we are able to aid and maintain the homeostatic balance supported by the skin’s endocannabinoid system.
Not convinced? See for yourself! Check out Allay’s own luxurious, potent, and ethically sourced CBD body butter, or read what our clients are saying.
Age beautifully- your way.
Is CBD lotion safe to use for arthritis symptoms?
The most common question people have when it comes to CBD lotions or cream for pain management or its anti-inflammatory properties is whether or not it is safe to use for arthritis symptoms.
Many or ALLAY consumers have concerns with additional potential and side effects (as they should be).
According to our own Chief Science Officer, Dr. Kellie Raydon and some top health experts and agencies, the answer is yes. It is safe to use. *See our video Dr. Kellie Raydon Chief Science officer.
For instance, Medscape shares that while cannabinoid medicine is still in its early stages, “unlike marijuana and THC, the risks associated with CBD are extremely low, with not a single case report of CBD overdose in the literature. The National Institute on Drug Abuse agrees and states that “CBD appears to be a safe drug with no addictive effects.” *See video below
In the future, it is likely that the Food and Drug Administration (FDA) will also begin to regulate CBD products, providing an additional safety net, as this agency indicates that “increasing public interest” in this substance increases the importance of establishing regulatory procedures.
We at Allay strive to bring the best product to our consumers, we are also committed to bringing answers to your questions, leave a comment and ask questions we are here to share and educate. Be sure to shop at our online shop www.allaytopical.com for our product and to gain more information about our product on our education page.
In my last two posts, I talked about the downfalls of the CBD boom and the necessity of product transparency. Readers learned what to look for when buying CBD, and how to stay safe in an age of misinformation.
SO! If you're crunched on time, too lazy to read the last two blogs (hey, no judgment!), or if you simply want a brief recap, here’s what you need to know:
(1) Make sure it's USDA certified organic and ethically sourced
The first thing you need to do is make sure your CBD product is derived from certified organic hemp.
Remember what I said about hemp being a bioaccumulator? That means it absorbs everything in the soil, including pesticides and toxins, at a faster rate that it is able to release or use them. If you’re concerned about pesticides, heavy metals, and other toxins, make sure that the oil you are buying is extracted from an organic plant.
It's also important to make sure your hemp is ethically grown, on US soil. Buying local, USDA certified hemp ensures that your product is pure and safe, while also supporting the local economy.
(2) Check the extraction method
Most of what you need to know will be covered in step three, finding a CofA. But if you aren't able to get your hands on one, or are crunched on time, you should at least check the extraction method. There are benefits and drawbacks to each method. For more information, check out my last blog.
(3) Get the lab results (aka the Certificate of Analysis (CofA))
Because of the gross lack of regulation in the CBD industry, companies are able to put whatever they’d like on the label. Remember the statistics from part 1 of this blog series? Out of 84 products from 31 different companies, nearly 70% were mislabeled (Bonn-Miller, et al. 2017).
A CofA ensures that the product was third-party tested, and is a great way to avoid fraudulent claims about potency and purity. Just look for the batch number of the product you’re looking to buy! At the end of this post, I've attached an example of Allay's most recent CofA- annotated to show exactly what to look for.
With a CofA, you’ll be able to find the following:
A CofA will show you exactly what pesticides, heavy metals, and toxic residue may still exist in the final product. CBD products that were extracted using butane, for example, can have toxic residue that may increase one’s risk of cancer. A CofA will also show you if there is any mold or bacteria in your product- just look for the “Microbiological Testing.”
Is what your buying really going to be effective? Is the money your spending really worth it, or will it be wasted on a weak product? You can find the total count of CBD, CBDa, CBN, and THC under “cannabinoid summary.” By looking at the full cannabinoid summary you can ensure that the product you are buying is truly full-spectrum, whole plant medicine.
And yep, that’s it. Just three steps! Buy organic, check the extraction method, and look for a CofA. All of this will ensure that your product is safe, accurately labeled, and potent.
Part 2: The importance of transparency
(and why Allay rocks☺)
On Monday I introduced Sanjay Gupta’s ‘Weed 5: The CBD Craze,’ which investigated the benefits and drawbacks of the new and booming CBD industry.
The problem, Gupta argues, is a lack of proper regulation leading to mislabeled, and occasionally harmful CBD products. There is, in other words, a blatant lack of transparency and honesty in the CBD market.
So, what can the consumer do to combat this?
How it’s made: Extraction, explained
First, it’s important to understand a little about how CBD oil is made. This is because the extraction process has everything to do with producing a clean and toxin-free final product. Not all CBD is created equal! When buying CBD it is crucial that the consumer pay attention to the specific method of extraction used to ensure that their product is clean, safe, and potent.
It all starts with the plant. The first thing to pay attention to is whether your CBD product is derived from certified organic hemp. Hemp is a bioaccumulator- this means that is absorbs all of the chemicals, pesticides, and toxins in the soil at a faster rate than it is able to use or release them. If a CBD product is extracted from non-organic hemp, it's going to carry all of those toxins, heavy metals, and pesticides with it. Yuck.
“As far as we’re concerned, there is only one way to grow anything: organically and sustainably. Because our soil is some of the richest, most fertile in the west, and because our climate is ideal for growing compelling cannabis, we let nature do her job. Every cultivation choice is based on bringing forth the perfection that is already inherent in the plants and on our farm” -Siskiyou Sungrown, Allay’s source of high quality CBD oil
There are two main extraction methods that consumers should look out for; CO2 extraction and Solvent extraction.
Simply put, supercritical CO2 extraction uses cooled and pressurized CO2 to draw out CBD and other phytochemicals.
At certain temperatures, CO2 becomes what is known as a 'supercritical liquid.' This means that it has the properties of both a gas and a liquid. In this state, CO2 acts as a solvent passing through porous solids and dissolving materials. Producers are able to fine tune which phytochemicals and compounds are extracted by controlling the pressure and temperature of the CO2.
This method is generally safe and clean, although it does have a few drawbacks. Namely, if the cannabis plant isn't dried adequately before hand, the final product may contain carcinogens and rancid fats. This method is also costly, and requires a lot of energy.
CO2 extracted products also lack a number of helpful phytochemicals (or active compounds). Because this method can only extract oil soluble compounds, the range of phytochemicals it is able to extract is limited. But more on this later...
Ethanol extraction typically involves decarbonating the plant (i.e. heating the plant to remove carbon atoms), and then soaking the plant in solvent- usually ethanol or butane- to extract its active compounds.
This method has its disadvantages. For one, using a solvent such as butane can leave behind toxic and harmful residue if the solvent isn't completely evaporated. Ethanol, on the other hand, is a natural solvent which works just as effectively as butane without the risk of toxins.
Because this process extracts both water soluble and oil soluble phytochemicals, the final product carries a wider range of helpful compounds. This includes compounds such as polyphenols, which can prevent degenerative disease, boost brain function and digestion, and more! The final product is truly full-spectrum, containing in it more helpful compounds than its CO2 derived counterpart.
Extracting with a solvent also creates ‘esters.’ These are water-soluble organic compounds, which replace hydrogen with a hydrocarbon group (Clark 2004). Because these compounds are water soluble, they have much higher bioavailability (that is- they are easier for our bodies to break down and digest!). Oil-soluble compounds, on the other hand, need to be broken down by our bodies acids and enzymes, making them difficult to digest. Reduced bioavailability means reduced potency!
Allay believes that ethanol extraction is the best method to ensure a clean, potent, and pure product. Siskiyou Sungrown uses only USP grade organic cane oil as a solvent, creating a product that is truly full-spectrum!
“ [...] Ethanol extracts both water soluble and oil soluble plant constituents very effectively. Consequently, hemp oil extracted with ethanol is truly full spectrum, exhibiting the synergy of all available beneficial phytochemicals. The ethanol that Siskiyou Sungrown uses for extraction is strictly USP grade, certified organic cane alcohol”
Remember Jay Jenkins from the last blog? The young man who almost died after consuming entirely synthetic, mislabeled CBD?
Companies aren’t always required to include all of the ingredients they put into their CBD. Manufacturers can add a number of different things to increase profit, including preservatives, non-cannabis derived terpenes, various food colorings, thinning agents, and more. A lot of this stuff can be harmful to your health. If a company isn’t transparent about what goes in to their final product, don’t buy it! A great way to make sure you’re being safe is to ask for the lab results of the final CBD product.
Radical. Transparency. That’s what we’re after here at Allay medicinals.
In my next post, I’ll give you all a quick recap of what this all means, and provide a succinct and easy-to-follow guide on how to buy CBD!
“CBD Oil Extraction Technique - Ethanol vs. Supercritical CO2.” CBD Oil Review, 2018, https://cbdoilreview.org/cbd-cannabidiol/ethanol-vs-supercritical-co2-extraction/#What-Is-Supercritical-CO2-Extraction?
Clark, Jim. “An Introduction to Esters.” Chem Guide, Sept. 2004, https://www.chemguide.co.uk/organicprops/esters/background.html.
Siskiyou Sungrown. “Ethanol extraction vs. CO2." Instagram, 27 Sept. 2019, https://www.instagram.com/p/B27OHaaFP3j/
A three part series on Sanjay Gupta,
CBD product transparency,
and how to navigate through it all.
Last week, Dr. Sanjay Gupta released his latest addition to "Weed," a documentary about cannabis's potential as medicine from the perspective of medical professionals, patients, and first hand accounts. The newest episode, "Weed 5: The CBD craze," breaks down everything you need to know about the new and booming industry of CBD. Gupta, in his trademark resolute style, looks at the story in its entirety- we see the miracles as well as the downfalls.
I want to offer a three part series, inspired by Sanjay Gupta’s latest documentary, about the wild world of CBD; the advantages and drawbacks of a rapidly booming industry, the necessity of transparency, and how to navigate through it all.
And yep, it's a little complicated. But have no fear! Companies like Allay are here to walk you through the process. This isn't about plugging a certain product. This about informing people, keeping people safe, and demonstrating the immense potential of cannabis as medicine when done correctly.
You can look forward to two follow-up blogs, 'Transparency' and ‘How to buy CBD,' on Wednesday 9th and Friday 11th respectively.
So, Who is Sanjay Gupta?
Sanjay Gupta is chief medical correspondent for CNN, and an avid supporter of the medical potential of cannabis. But it hasn’t always been that way- before airing the first installment of ‘Weed,’ Sanjay was skeptical. It was his steadfast commitment to science, regardless of personal or political leanings, regardless of faith or belief, which lead him to see its potential. In ‘Weed 5’ Sanjay pushes back against the term ‘advocate.’ This is because, for Sanjay, CBD is more than its accompanying political narrative. It is more than something to rally behind so long as it adheres to your personal philosophy. The fact that CBD and Cannabis have immense medical potential is a scientific truth.
“Make no mistake” Sanjay states in an Op-ed accompanying the series, “Cannabis is a medicine.”
The Wild West of CBD
Since 2013, when the first episode of ‘Weed’ aired, we have seen a massive growth in popularity concerning medical marijuana and CBD products. CBD will soon be a $22 billion dollar industry, with CBD products being sold in coffee shops, grocery stores, bars, and more (Dorbian 2019).
This stuff is everywhere. But is this really a good thing?
Thanks to the rising popularity of cannabis as medicine, there have been countless success stories.
In “Weed: 5,” Gupta got an exclusive look at GW pharmaceuticals’ own cannabis greenhouses, where they are extracting and selling CBDV (another non-psychoactive cannabidiol found in cannabis plants) as a treatment for epilepsy, and potentially autism. In an earlier op-ed, titled “Why I Changed My Mind on Weed,” Gupta tells the story of Charlotte Figi- a young girl whose seizures were reduced significantly after consuming a high-CBD cannabis oil (Rashidian 2019). Individual accounts of CBD helping with anything from seizures, to anxiety, to muscle pain are innumerable.
But the stories aren’t always so bright.
Gupta also interviewed a young man named Jay Jenkins. Within seconds of consuming what he thought was CBD oil Jenkins started severely hallucinating, eventually losing consciousness. At the hospital Jenkins scored a 3 on the Glasgow Coma Scale- he was in critical condition.
It turns out that what Jenkins had tried was not CBD at all, but an entirely synthetic product marketed and sold as CBD.
This is where the problem lies. Without adequate regulation in most states, there is nothing requiring these products to be tested, safe, and authentic. One study found that out of 84 CBD products from 31 different companies, 69% were mislabeled (Bonn-Miller, et al. 2017). Although this study was conducted in 2017, recent studies show that not much has changed (Grubb 2019). Other studies found that some CBD products contain dangerous synthetics.
“CBD has been hijacked by unscrupulous actors peddling crooked, corrupt, and
Consumers are lost in a wild, unregulated world. Finding a trustworthy product- knowing what goes in to it, feeling confident that you are making a healthy choice, knowing what to look for when buying CBD, has become increasingly difficult. It is, as Gupta says,
“a bold promise, hijacked.”
Stayed tuned for more blogs about the importance of transparency in an age of confusion and misinformation. Allay is dedicated to providing clients sustainably sourced, full spectrum cbd that is guaranteed to work.
No empty promises,
no snake-juice cure-alls,
just pure, consciously derived, effective cbd products.
Bonn-Miller, Marcel O, et al. “Labeling Accuracy of Cannabidiol Extracts Sold Online.” JAMA, American Medical Association, 7 Nov. 2017, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5818782/.
Dorbian, Iris. “CBD Market Could Reach $20 Billion By 2024, Says New Study.” Forbes, Forbes Magazine, 20 May 2019, https://www.forbes.com/sites/irisdorbian/2019/05/20/cbd-market-could-reach-20-billion-by-2024-says-new-study/#7a6b09cc49d0.
Grubb, Bill. “Noramco Cannabidiol FDA Presentation.” US Food and Drug Administration , 31 May 2019, pp. 4–10 . Noramco.
Gupta, Sanjay. “CNN Health.” CNN Health, WarnerMedia, 27 Sept. 2019, https://edition.cnn.com/2019/09/27/health/weed-5-cbd-craze-gupta/index.html.
Rashidian, Nushin. “Q&A: Three Questions for Sanjay Gupta on CBD.” Cannabis Wire, 27 Sept. 2019, https://cannabiswire.com/2019/09/27/qa-three-questions-for-sanjay-gupta-on-cbd/.